Indications
Approved Uses Otezla® (apremilast) is a prescription medicine used to treat adult patients with:
  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate. Read more >
Approved Uses Otezla® (apremilast) is a prescription medicine used to treat adult patients with:
  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Active psoriatic arthritis.
  • Oral ulcers associated with Behçet’s Disease. Read less >

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No matter where you are in your treatment journey, we’re here to help every step of the way

Considering Otezla?
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Get Otezla information and resources for your upcoming appointment(s)

Already have an Otezla prescription?

Through Amgen® SupportPlus, you can enroll in the $0 Co-Pay* Program to help lower your out of pocket costs, and access dedicated Amgen Nurse Partner support and resources to help you start and stay on track with treatment.

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*Only for commercially insured patients. Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.
Amgen Nurse Partners are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. You will be referred to your doctor’s office for clinical advice

Whether you are considering Otezla or have been recently prescribed, you can sign up today for more information Thanks for signing up

*Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.
Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.
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Please fill out this form to enroll in Amgen® SupportPlus and more.
You’re almost done! If you have your prescription insurance information, please fill out the fields below.

All fields are required unless indicated as optional.

Choose your condition:
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The Otezla Co-Pay Card can help reduce out-of-pocket costs for eligible commercially insured patients.
Are you eligible for Medicare but receive prescription drug coverage from a former employer, union, or welfare plan?
By checking this box, I agree that I read, understand, and accept the Terms and Conditions of the Otezla Co-Pay Card
If you have Medicare or Medicaid coverage, our team of Amgen SupportPlus Representatives can assist you with any questions you may have about your plan. Our team is knowledgeable in Medicaid and can also review the Medicare Part D plan phases to help you understand what you can anticipate.
The Amgen Safety Net Foundation is a nonprofit patient assistance program sponsored by Amgen that helps qualifying patients access Amgen medicines at no cost. Their contact information will be provided after your enrollment is complete.
Our team of Amgen SupportPlus Representatives may be able to help you figure out how to lower your out-of-pocket costs for Otezla. Their contact information will be provided after your enrollment is complete.
Amgen Nurse Partners are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. You will be referred to your doctor’s office for clinical advice.
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Please fill out your prescription insurance information to complete your enrollment in the $0 Co-Pay Program.*

You are now signed up to learn the ins and outs of treatment with Otezla. Keep an eye on your email for more helpful information.

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Patient stories

Otezla has helped hundreds of thousands of people like you.
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You are now signed up to learn the ins and outs of treatment with Otezla. Keep an eye on your email for more helpful information.

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What to expect on Otezla

Find out about managing side effects, seeing results, and more.

Your physical card will arrive through the mail in a few days, but you can start paying as little as $0* today.

You’re on your way. Here’s how to get started in 2 simple steps:

Share the following information with your specialty pharmacy
Share the following information with your specialty pharmacy
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Once the pharmacist has your co-pay card information, it will be automatically applied each time you fill your Otezla prescription.
Your Otezla prescription will be delivered right to your
                        door
Your Otezla prescription will be delivered right to your door
Questions? Our Otezla team members are available
Monday – Friday, 8AM – 8PM ET, at 1-844-4OTEZLA (1-844-468-3952) to help you.
We’re with you along the way,
Your Otezla Team
*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.
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Amgen SupportPlus provides assistance with everything from prior authorization to treatment questions. Keep an eye on your email for more helpful information.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

The most common side effects of Otezla include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla.

APPROVED USES

Otezla® (apremilast) is a prescription medicine used to treat adult patients with:

  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Active psoriatic arthritis.
  • Oral ulcers associated with Behçet’s Disease.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing,