Otezla® Commercial | Otezla® (apremilast) for Psoriasis
Indications
Approved Uses Otezla® (apremilast) is a prescription medicine used for the treatment of:
  • Adult patients with plaque psoriasis for whom phototherapy or systemic therapy is appropriate. Read more >
Approved Uses Otezla® (apremilast) is a prescription medicine used for the treatment of:
  • Adult patients with plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Pediatric patients 6 years of age and older and weighing at least 20 kg with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • Adult patients with active psoriatic arthritis.
  • Adult patients with oral ulcers associated with Behçet’s Disease. Read less >

Live in the moment.

Not in your head.

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Otezla can help you achieve clearer skin after just 4 months.

Is the thought of itchy red patches taking you out of the moment? Take a look at the latest Otezla commercial.

Watching in public? Speakers won’t connect? No worries, you can read the transcripts below.

  • Transcript

    On-screen Text:

    For adult patients with plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

    Voiceover Announcer:

    Ned’s excited for his big date. But he’s wondering…

    Ned:

    What if a flaky plaque throws me off my game?

    Voiceover Announcer:

    What if Ned knew he could treat differently?

    Narrator:

    Otezla is the #1 prescribed pill to treat plaque psoriasis.

    Ned’s Date:

    Ned?

    Narrator:

    Otezla can help you get clearer skin, and reduce itching and flaking.

    On-screen Text:

    Get clearer skin with Otezla after just four months.

    Individual results may vary.

    Narrator:

    Doctors have been prescribing Otezla for over a decade.

    On-screen Text:

    Doctors have been prescribing Otezla for over a decade

    Narrator:

    Don’t use Otezla if you’re allergic to it. Get medical help right away if you have trouble breathing or swallowing, swelling of the face, lips, tongue, throat or arms.

    On-screen Text:

    Don’t use Otezla if you’re allergic to it. Get medical help right away if you have trouble breathing or swallowing, swelling of the face, lips, tongue, throat or arms

    Narrator:

    Severe diarrhea, nausea, or vomiting; depression, suicidal thoughts or weight loss can happen. Tell your doctor if any of these occur, and if you have a history of depression or suicidal thoughts.

    On-screen Text:

    Severe diarrhea, nausea, or vomiting; depression, suicidal thoughts or weight loss can happen. Tell your doctor if any of these occur, and if you have a history of depression or suicidal thoughts.

    Voiceover Announcer:

    With clearer skin, movie night is a groovy night.

    Live in the moment. Ask your doctor about Otezla.

    On-screen Text:

    Otezla®
    Live in the moment. Ask your doctor about Otezla

    For more information about cost, visit Otezla.com or call
    1-844-4OTEZLA

    © 2025 Amgen Inc. All rights reserved. Amgen®

Pay as little as $0*

Did you know you may be eligible to pay as little as $0 per month through the Otezla Co-Pay Program? For eligible, commercially insured patients, your co-pay can be applied to deductible, co-insurance, and co-payment,* and is available regardless of your income level.

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First-time co-pay card user? Find out more about how it works, and how it can help.

No insurance? Learn about other ways to access Otezla.

*For commercially insured patients only. Eligibility criteria and program maximums apply.
See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.

Caregivers of kids and teens under 18 can contact Amgen® SupportPlus at
1-844-4OTEZLA (1-844-468-3952) to complete enrollment, Monday – Friday, 8 AM – 8 PM ET.
Hand holding copay card from Amgen® SupportPlus program
Hand holding copay card from Amgen® SupportPlus program
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Why consider Otezla?

Read about the benefits of Otezla for plaque psoriasis. Talk to your doctor to see if it’s right for you.
SEE THE BENEFITS
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Real patient experiences

Otezla has made a difference in lives of people just like you.
SEE THEIR STORIES

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla. For children 6 years of age or older, their doctor should monitor their growth (height and weight). If they are not growing or gaining weight as expected, their doctor will decide if they should continue taking Otezla.

Some medicines may make Otezla less effective and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

The most common side effects of Otezla include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla.

APPROVED USES

Otezla® (apremilast) is a prescription medicine used for the treatment of:

  • Adult patients with plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Pediatric patients 6 years of age and older and weighing at least 20 kg with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • Adult patients with active psoriatic arthritis.
  • Adult patients with oral ulcers associated with Behçet’s Disease.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing,