Otezla® Commercial: Live in the Moment | Otezla® (apremilast) for PsO
Indications
APPROVED USES Prescription Otezla®/Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis. Read more >
Approved Uses Prescription Otezla®/Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis.
  • OTEZLA XR: Adult and pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with active psoriatic arthritis.

Plaque Psoriasis:

  • OTEZLA/OTEZLA XR: Adult patients with plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA: Pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA XR: Pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

Oral Ulcers Associated with Behçet’s Disease:

  • OTEZLA/OTEZLA XR: Adult patients with oral ulcers associated with Behçet’s Disease. Read less >

Live in the moment.

Not in your head.

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Otezla can help you achieve clearer skin after just 4 months.

Tired of singing the same tune with your plaque psoriasis treatment? Take a look at the latest Otezla commercial.

Watching in public? Speakers won’t connect? No worries, you can read the transcripts below.

  • Transcript

    On-screen Text:

    For adult patients with plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

    On-screen Text:

    Welcome to the team Ned! Ready for karaoke on Friday?!?

    Voiceover Announcer:

    Coming to the stage this Friday its Ned’s first team karaoke night. But he’s wondering…

    Ned:

    What if my flaky, red plaque psoriasis takes center stage?

    Karaoke Announcer:

    Next up we have, Ned!

    Singer:

    🎶ITCHY, FLAKY, PLAQUEY OOH…ITCHY, FLAKY PLAQUEY OOH…ITCHY, FLAKY, PLAQUEY🎶

    Voiceover Announcer:

    What if Ned knew he could treat differently?

    Narrator:

    Otezla is a pill that treats plaque psoriasis…even in hard to treat areas.

    On-screen Text:

    Get clearer skin with Otezla after just 4 months. Individual results may vary. Doctor prescribed for over 10 years.

    Narrator:

    You can get clearer skin and reduce itching and flaking. Doctors have been prescribing Otezla for over 10 years.

    On-screen Text:

    Don’t use Otezla if you’re allergic to it. Get medical help right away if you have trouble breathing or swallowing, swelling of the face, lips, tongue, throat or arms.

    Narrator:

    Don’t use Otezla if you’re allergic to it. Get medical help right away if you have trouble breathing or swallowing, swelling of the face, lips, tongue, throat or arms.

    On-screen Text:

    Don’t use Otezla if you’re allergic to it. Get medical help right away if you have trouble breathing or swallowing, swelling of the face, lips, tongue, throat or arms.

    Narrator:

    Severe diarrhea, nausea, or vomiting; depression, suicidal thoughts or weight loss can happen. Tell your doctor if any of these occur, and if you have a history of depression or suicidal thoughts.

    On-screen Text:

    Severe diarrhea, nausea, or vomiting; depression, suicidal thoughts or weight loss can happen. Tell your doctor if any of these occur, and if you have a history of depression or suicidal thoughts.

    Voiceover Announcer:

    With Otezla, clearer skin could be your jam.

    Live in the moment. Struggling on topicals? Ask your doctor about Otezla.

    On-screen Text:

    ASK YOUR DOCTOR ABOUT
    Otezla logo QR code
    Scan to learn more

    For more information about cost, visit Otezla.com or call 1-844-4OTEZLA

    Amgen logo ©2025 Amgen Inc. All rights reserved.

Pay as little as $0*

Did you know you may be eligible to pay as little as $0 per month with the Otezla Co-Pay Program? For eligible, commercially insured patients, your co-pay can be applied to deductible, co-insurance, and co-payment,* and is available regardless of your income level.

Enroll Now

First-time co-pay card user? Find out more about how it works and how it can help.

No insurance? Learn about other ways you may be able to access Otezla as prescribed.

*For commercially insured patients only. Eligibility criteria and program maximums apply.
See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.

Caregivers of kids and teens under 18 can contact Amgen® SupportPlus at
1-844-4OTEZLA (1-844-468-3952) to complete enrollment, Monday – Friday, 8 AM – 8 PM ET.
Hand holding copay card from Amgen® SupportPlus program
Hand holding copay card from Amgen® SupportPlus program
Group of friends dancing at a party

Why consider Otezla?

Read about the benefits of Otezla for plaque psoriasis. Talk to your doctor to see if it’s right for you.
SEE THE BENEFITS
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Real patient experiences

Otezla has made a difference in lives of people just like you.
SEE THEIR STORIES

IMPORTANT SAFETY INFORMATION

Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR

Otezla/Otezla XR can cause serious side effects, including:

  • Allergic reactions, sometimes severe. Stop using Otezla/Otezla XR and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.
  • Severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla/Otezla XR may increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.
  • Depression. In clinical studies, some patients reported depression or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla/Otezla XR, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla/Otezla XR.
  • Weight loss. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla/Otezla XR. For children 6 years of age or older, their doctor should monitor their growth (height and weight). If they are not growing or gaining weight as expected, their doctor will decide if they should continue taking Otezla/Otezla XR.

Some medicines may make Otezla/Otezla XR less effective and should not be taken with Otezla/Otezla XR. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines.

The most common side effects include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla/Otezla XR. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla/Otezla XR.

APPROVED USES

Prescription Otezla® /Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis
  • OTEZLA XR: Adult and pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with active psoriatic arthritis.

Plaque Psoriasis:

  • OTEZLA/OTEZLA XR: Adult patients with plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA: Pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA XR: Pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

Oral Ulcers Associated with Behçet’s Disease:

  • OTEZLA/OTEZLA XR: Adult patients with oral ulcers associated with Behçet’s Disease.

IMPORTANT SAFETY INFORMATION

Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR.

Otezla/Otezla XR can cause serious side effects, including:

  • Allergic reactions, sometimes severe. Stop using Otezla/Otezla XR and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.