*Certain restrictions apply. *Certain restrictions apply; eligibility not based on income.

Treat plaque psoriasis differently

Treat psoriatic arthritis differently

FOR US AUDIENCES ONLY
SEE MORE

*Certain restrictions apply. *Certain restrictions apply; eligibility not based on income.

Approved Uses

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

Important Safety Information

You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.

Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.

These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088. 1-800-332-1088.

Please click here for Full Prescribing Information.

Types of Treatment for Plaque Psoriasis

Though many people assume that plaque psoriasis is "just a skin disease," it actually starts inside the body—so it's important to treat with that in mind.

If you’ve been living with plaque psoriasis for a while, you and your dermatologist have probably tried a lot of different things to treat it. Most (though not all) treatments for plaque psoriasis fall into 2 categories: systemic or non-systemic. Systemic treatments are generally taken as pills or injections. Non-systemic treatments are generally applied directly to the skin’s surface.

Systemic Treatments

Treatments that work inside the body to help reduce plaque psoriasis symptoms. Systemic medications include:

  • Oral medications: Pills, tablets, or capsules taken by mouth. Otezla® (apremilast) is one of these.
  • Injectable biologics: Medications that are injected into the body to act on a specific function of the immune system.

Non-systemic treatments

Treatments that are applied to the skin's surface to help reduce plaque psoriasis symptoms.

Non-systemic medications include:

  • Topical medications: Creams, lotions, and salves that are applied to the skin's surface to help reduce symptoms.
  • Phototherapy: Also known as light therapy, phototherapy involves exposing the skin to ultraviolet light on a regular basis.

Otezla Is Different

If your plaque psoriasis isn’t responding to topical treatments as well as you would like, or if you are seeking options, it may be time for you and your doctor to consider something different.

Otezla is the only PDE4 inhibitor approved to treat moderate to severe plaque psoriasis. Otezla works inside the body to help reduce inflammation. For people with plaque psoriasis, less skin inflammation is thought to result in fewer skin cells piling up, and fewer plaques.

Learn about the side effects of Otezla

4 REASONS TO CONSIDER OTEZLA

1Otezla is a pill—not a cream, biologic, or an injection.
2Otezla works from inside the body to help reduce inflammation.
3The Otezla Prescribing Information has no requirement for ongoing lab monitoring or initial lab testing.
4With the $0 co-pay* offer, eligible people can get Otezla at no out-of-pocket cost.

*Certain restrictions apply; eligibility not based on income.

“The topical therapies didn’t work on my plaque psoriasis symptoms.”

—JenniferActual Otezla patient

See Jennifer’s story
Otezla is a different kind of treatment Close

Approved Uses

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

SEE MORE

*Certain restrictions apply. *Certain restrictions apply; eligibility not based on income.

Approved Uses

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

Important Safety Information

You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.

Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.

These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088. 1-800-332-1088.

Please click here for Full Prescribing Information.

Important Safety Information

See more

You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

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