Benefits of Otezla® (apremilast) | Plaque Psoriasis (PsO)
Indications
APPROVED USES Prescription Otezla®/Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis. Read more >
Approved Uses Prescription Otezla®/Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis.
  • OTEZLA XR: Adult and pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with active psoriatic arthritis.

Plaque Psoriasis:

  • OTEZLA/OTEZLA XR: Adult patients with plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA: Pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA XR: Pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

Oral Ulcers Associated with Behçet’s Disease:

  • OTEZLA/OTEZLA XR: Adult patients with oral ulcers associated with Behçet’s Disease. Read less >

Why consider Otezla

for plaque psoriasis?

Otezla is a pill approved for plaque psoriasis across all severities. Talk to your doctor to see if it’s right for you.

Genine Actual Otezla patient
compensated for her time

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A few things to know about Otezla, the #1 prescribed pill for plaque psoriasis:*

Reduce redness, itching, and flaking
Plaque psoriasis patches and plaques on arm
Achieve clearer skin after just 4 months even in hard to treat areas.
SEE BEFORE & <br>AFTER PHOTOS<span><img src="/-/media/F1E61FAEC4E64EFFA694854C8983049E.ashx"/></span>
Established safety record
No blood tests for Otezla® (apremilast)
You can start Otezla right away—no blood tests required.
READ ABOUT <br>OTEZLA SAFETY<span><img src="/-/media/F1E61FAEC4E64EFFA694854C8983049E.ashx"/></span>
Real results with Otezla
More than 1 million Otezla® (apremilast) patients
More than 1 million people have been treated with Otezla globally.† Get to know just a few of these people just like you.
HEAR THEIR <br>STORIES<span><img src="/-/media/F1E61FAEC4E64EFFA694854C8983049E.ashx"/></span>
Goes where topical treatments can’t
Example of PDE4 inhibitor

No needle. No mess.
Unlike some topicals, Otezla tackles symptoms from the inside where inflammation starts.

HOW DOES <br>OTEZLA WORK?<span><img src="/-/media/F1E61FAEC4E64EFFA694854C8983049E.ashx"/></span>
*According to an observational study performed from January 2018 to December 2023 using Longitudinal Access and Adjudication Dataset (LAAD) claims data obtained from IQVIA and extracted for oral treatments with a plaque psoriasis indication.
†Estimates of patients treated reflect global data since launch (Apr 2014-Mar 2024; US=59% of data). Calculations based on observed drug utilization parameters and number of units distributed. Utilization patterns change over time to best represent current markets.
Enroll in the co-pay program before leaving your doctor's office

In a study of adults with mild to moderate plaque psoriasis,

Enroll Now
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Prepare for your appointment

Communication is key. Start the conversation.
PREPARE FOR YOUR APPOINTMENT

Pay as little as $0*

Did you know you may be eligible to pay as little as $0 per month with the Otezla Co-Pay Program? For eligible, commercially insured patients, your co-pay can be applied to deductible, co-insurance, and co-payment,* and is available regardless of your income level.

Enroll Now

First-time co-pay card user? Find out more about how it works and how it can help.

No insurance? Learn about other ways you may be able to access Otezla as prescribed.

*For commercially insured patients only. Eligibility criteria and program maximums apply.
See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.

Caregivers of kids and teens under 18 can contact Amgen® SupportPlus at
1-844-4OTEZLA (1-844-468-3952) to complete enrollment, Monday – Friday, 8 AM – 8 PM ET.
Hand holding copay card from Amgen® SupportPlus program
Hand holding copay card from Amgen® SupportPlus program

DALLAS' STORYDALLAS GOEDERT + OTEZLA

PAT’S STORYPAT + OTEZLA

CINDY’S STORYCINDY + OTEZLA

MICHAEL’S STORYMICHAEL + OTEZLA

KAYLA’S STORYKAYLA + OTEZLA

SARAH’S STORYSARAH + OTEZLA

CHARLIE’S STORYCHARLIE + OTEZLA

JILLIAN’S STORYJILLIAN + OTEZLA

Fox Sports Radio Hosts Try to Beat Pro Football
Champion and Real Otezla Patient Dallas Goedert’s
football stats while putting up with some distractions.

GENINE'S STORYGENINE + OTEZLA

REBECCA'S STORYREBECCA + OTEZLA

Genine-image

Meet Genine

For Genine, treating itchy, flaky scalp psoriasis used to mean applying greasy oils and creams each night which took away from spending time with family. When plaque psoriasis showed up on her fingernails, she and her doctor had a conversation about treating plaque psoriasis differently— from the inside-out, with a pill. With Otezla, Genine is happy to have seen clearer skin after just four months with a treatment routine that better fits her lifestyle, and helps her make time for the things she loves.

Your results may vary.

*Patients have been compensated for their time.

Your results may vary.

rebecca_crousel_img

Meet Rebecca

Rebecca was in college when she first saw plaque psoriasis appear on her face. From there, she was prescribed topical treatment after topical treatment, and their greasiness made it challenging to have a certain skincare routine or wear the clothes she wanted. Rebecca shared this with her doctor, who recommended a pill called Otezla. Rebecca is happy to have a plaque psoriasis treatment that works for her lifestyle and would encourage others to talk to their doctor sooner.

Your results may vary.

*Patients have been compensated for their time.

Your results may vary.

IMPORTANT SAFETY INFORMATION

Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR

Otezla/Otezla XR can cause serious side effects, including:

  • Allergic reactions, sometimes severe. Stop using Otezla/Otezla XR and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.
  • Severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla/Otezla XR may increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.
  • Depression. In clinical studies, some patients reported depression or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla/Otezla XR, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla/Otezla XR.
  • Weight loss. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla/Otezla XR. For children 6 years of age or older, their doctor should monitor their growth (height and weight). If they are not growing or gaining weight as expected, their doctor will decide if they should continue taking Otezla/Otezla XR.

Some medicines may make Otezla/Otezla XR less effective and should not be taken with Otezla/Otezla XR. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines.

The most common side effects include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla/Otezla XR. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla/Otezla XR.

APPROVED USES

Prescription Otezla® /Otezla XRTM (apremilast) is used for the treatment of:

Active Psoriatic Arthritis:

  • OTEZLA: Adult and pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with active psoriatic arthritis
  • OTEZLA XR: Adult and pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with active psoriatic arthritis.

Plaque Psoriasis:

  • OTEZLA/OTEZLA XR: Adult patients with plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA: Pediatric patients 6 years of age and older and weighing at least 20 kg (44 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.
  • OTEZLA XR: Pediatric patients 6 years of age and older and weighing at least 50 kg (110 lbs) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

Oral Ulcers Associated with Behçet’s Disease:

  • OTEZLA/OTEZLA XR: Adult patients with oral ulcers associated with Behçet’s Disease.

IMPORTANT SAFETY INFORMATION

Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR.

Otezla/Otezla XR can cause serious side effects, including:

  • Allergic reactions, sometimes severe. Stop using Otezla/Otezla XR and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.