×
There are updates to the co-pay card. If you are having issues using your co-pay card, click here for more information.
Benefits of Otezla® (apremilast) for Plaque Psoriasis
Indications
Approved Uses Otezla® (apremilast) is a prescription medicine used to treat adult patients with:
  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate. Read more >
Approved Uses Otezla® (apremilast) is a prescription medicine used to treat adult patients with:
  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Active psoriatic arthritis.
  • Oral ulcers associated with Behçet’s Disease. Read less >

Why consider Otezla

for plaque psoriasis?

Otezla is a pill that can help you tackle plaque psoriasis.
Talk to your doctor to see if it’s right for you.

You are leaving the Otezla website

Do you wish to leave this site?

YES No
#1

Otezla is the #1 prescribed pill to treat plaque psoriasis*

Plaque psoriasis patches and plaques on arm
Achieve clearer skin after just 4 months with reduced redness, itchiness, and flaking
SEE RESULTS
No blood tests for Otezla® (apremilast)
Some other medications for plaque psoriasis require blood tests, Otezla does not.
READ ABOUT OTEZLA SAFETY
840k+
The numbers don’t lie—over 840,000 people have taken Otezla†
HEAR THEIR STORIES
Example of PDE4 inhibitor
Otezla works inside the body to treat symptoms where they start
HOW DOES OTEZLA WORK?
*According to an observational study performed from January 2018 to December 2022 using National Prescription Audit data obtained from IQVIA and extracted for oral treatments with a plaque psoriasis indication.
†Estimates of patients treated reflect global data since launch (Apr 2014-Mar 2023; US=approximately 60% of data). Calculations based on observed drug utilization parameters and number of units distributed. Utilization patterns change over time to best represent current markets.

I don’t feel the need to hide anymore.”

Sarah Actual Otezla patientClick here to read more of Sarah’s story.

A woman holding a yellow balloon over her face
Three women taking a picture at brunch

See before and after photos

Discover the difference Otezla can make.
TAKE A LOOK

Pay as little as $0*

The Otezla Co-Pay Program may help eligible patients with commercial insurance (usually self-purchased or through an employer) lower their out-of-pocket costs for Otezla.

  • Pay as little as $0* out-of-pocket for each dose
  • Can be applied to deductible, co-insurance, and co-payment*
  • Support available regardless of income level
SIGN UP

First time using a co-pay card? Find out more about how it can help you.

No insurance? Learn about other ways to access Otezla.

*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.
Hand holding copay card from Amgen® SupportPlus program
Woman on her laptop, in bed

Patient stories

Otezla has helped hundreds of thousands of people like you.
DISCOVER HOW

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

The most common side effects of Otezla include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla.

APPROVED USES

Otezla® (apremilast) is a prescription medicine used to treat adult patients with:

  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.
  • Active psoriatic arthritis.
  • Oral ulcers associated with Behçet’s Disease.

IMPORTANT SAFETY INFORMATION

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing,