Active Psoriatic Arthritis:
Active Psoriatic Arthritis:
Plaque Psoriasis:
Oral Ulcers Associated with Behçet’s Disease:
If you and your doctor have decided to start Otezla, understanding how to pay for your treatment is an important next step.
Did you know you may be eligible to pay as little as $0 per month with the Otezla Co-Pay Program? For eligible, commercially insured patients, your co-pay can be applied to deductible, co-insurance, and co-payment,* and is available regardless of your income level.
First-time co-pay card user? Find out more about how it works and how it can help.
No insurance? Learn about other ways you may be able to access Otezla as prescribed.
*For commercially insured patients only. Eligibility criteria and program maximums apply.
See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.


A co-pay (or co-payment) is a flat fee that is paid each time a patient goes to a doctor or fills a prescription. The Otezla Co-Pay Program helps reduce that fee.
Patients with commercial insurance (self-purchased or through an employer) usually pay what is called the “out-of-pocket” cost for Otezla. This is the amount they owe after their insurance coverage has kicked in and any co-pays or deductibles have been applied.
Whether you were just prescribed Otezla or have been on Otezla, you can enroll in the Otezla Co-Pay Program today. Once you have enrolled, you’ll receive a digital co-pay card via email. Share your co-pay information with your specialty pharmacy to begin lowering your out-of-pocket costs. Eligible, commercially insured patients may pay as little as $0 per month for Otezla.
The pharmacy can apply the Otezla Co-Pay Card benefit (automatically) each month up to the annual maximum benefit of the co-pay program.
*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.
Signing up is simple, just fill out the form at Otezla.com/enroll, and if you’re eligible, you’ll automatically be enrolled. Once you have enrolled, you’ll receive a digital co-pay card via email. Share the co-pay information with your specialty pharmacy to begin lowering your out-of-pocket costs.
The Otezla Co-Pay Card is available to eligible patients with commercial insurance (usually self-purchased or through an employer) regardless of income level.
Re-enrollment in the program is required at regular intervals. You may continue in the program as long as you re-enroll as required by Amgen and continue to meet all of the program’s eligibility requirements during participation in the program.
If at any point a patient’s insurance changes, their enrollment in the program may be re-evaluated. They must continue to meet the program’s eligibility requirements to continue receiving benefits.
People usually pay what is called the “out-of-pocket” cost for Otezla. This is the amount they owe after their insurance coverage has kicked in and any co-pays or deductibles have been applied.
Commercially insured patients† can pay as little as $0 for Otezla when enrolled in the Otezla Co-Pay Program.
Signing up is simple, just fill out the form, and if you’re eligible, you’ll automatically be enrolled. Once you have enrolled, you’ll receive a digital co-pay card via email. Share the co-pay information with your specialty pharmacy to begin lowering your out-of-pocket costs.
The Otezla Co-Pay Program is available to eligible patients with commercial insurance (usually self-purchased or through an employer) regardless of income level.
Amgen SupportPlus Representatives can help you understand your current Medicare insurance plan and anticipated out-of-pocket costs for Otezla. If you want to switch Medicare plans, we can help identify other local options. We may also be able to refer you, if eligible, for Medicare Extra Help (Low Income Subsidy) or put you in touch with independent nonprofit foundations.‡
Please contact Amgen SupportPlus at 1-844-4OTEZLA (1-844-468-3952). Our team is here and ready to help Monday-Friday, 8 AM-8 PM ET.
‡Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofit’s criteria. Amgen has no control over these programs and provides information as a courtesy only.
If you are eligible, Amgen SupportPlus Representatives can provide information about independent nonprofit foundations that may be able to help.‡ Click here to get started by enrolling in Amgen SupportPlus or by calling 1-844-4OTEZLA (1-844-468-3952).
‡Eligibility for resources provided by independent nonprofit patient assistance programs is based on the nonprofit’s criteria. Amgen has no control over these programs and provides information as a courtesy only.
Our team of Amgen SupportPlus Representatives may be able to help you figure out how to lower your out-of-pocket costs for Otezla. Call Amgen SupportPlus at 1-844-4OTEZLA (1-844-468-3952), Monday – Friday from 8 AM to 8 PM ET.



Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR
Otezla/Otezla XR can cause serious side effects, including:
Some medicines may make Otezla/Otezla XR less effective and should not be taken with Otezla/Otezla XR. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines.
The most common side effects include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla/Otezla XR. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.
Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.
Please click here for the Full Prescribing Information for Otezla/Otezla XR.
Prescription Otezla® /Otezla XRTM (apremilast) is used for the treatment of:
Active Psoriatic Arthritis:
Plaque Psoriasis:
Oral Ulcers Associated with Behçet’s Disease:
Do not take Otezla 30 mg tablets or Otezla XR 75 mg extended-release tablets if you are allergic to apremilast or to any of the ingredients in Otezla/Otezla XR.
Otezla/Otezla XR can cause serious side effects, including: